Our models suggest new #COVID19 wave&new SARSCoV2 variants cases spread proving ineffective or short duration vaccines vs new variants continue to spread through 2021 and culminate by summer 2022 due to vaccine failure, new mutations escaping vaccine induced immunity, increased cases of immune system failure and long term effects, while vaccines provide near term false sense of security among vaccinated and overall lack of precautions due to covid fatigue. Coronavirus research was supervised by the NIAID, NIH, CDC who were all deeply involved and aware of poor outcome for covid vaccine efficacy and monoclonal antibodies due to mutability and adaptability since at least 2014.